Nemi hormon kötőfehérje (SHBG)
Más néven:
Hivatalos név:
Nemi hormon kötőfehérje
Másnéven: 25-Hidroxi-D vitamin (Kalcidiol); 1.25 Dihidroxi-D vitamin (Kalcitriol)
012.  A cikk utoljára módosult: 27.10.2017.
Mire való a vizsgálat?

Férfiakban leggyakrabban az alacsony tesztoszteron (androgén hiány) kivizsgálása során mérik, de szintén gyakran használatos az olyan nők kivizsgálásában, akik férfi nemi hormon (androgének) túlprodukció jeleit és tüneteit mutatják.

Mikor kell a vizsgálatot elvégezni?

Amikor Önnek emelkedett vagy csökkent tesztoszteron szintre jellemző tünetei vannak és a total (össz) tesztoszteron mérés eredménye nincs összhangban az Ön tüneteivel.

Milyen mintára van szükség?

A kar könyökhajlati vénájából vett vérmintára.

Hogyan készüljek elő a vizsgálatra?

Nincs szükség előkészületre.

Áttekintés

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Vizsgálat

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Gyakori kérdések

Mire való a vizsgálat?
Mikor kéri az orvos a vizsgálatot?
Mit jelent a vizsgálati eredmény?
Mit kell még tudnom?
Van-e más felhasználása az SHBG tesztnek?
Mi az a szabad androgén index (FAI)?

Kapcsolódó oldalak

Laboratóriumi vizsgálatok
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Állapotok és betegségek
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Máshol az interneten

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Felhasznált irodalom

Aktuális áttekintésben használt források

Reviewer May 2015: Nicole V. Tolan, PhD, DABCC, Associate Director of Chemistry and POCT, BIDMC and Harvard Medical School.

Isbell TS, Jungheim E, Gronowski AM. Reproductive endocrinology and related disorders. In: Burtis CA, Ashwood ER, Burns DE, eds. Tietz textbook of clinical chemistry and molecular diagnostics, Vol. 5th ed: Elsevier, 2012.

Pugeat M, Crave JC, Tourniaire J, Forest MG. Clinical utility of sex hormone-binding globulin measurement. Horm Res 1996;45:148-55.

Wheeler MJ. The determination of bio-available testosterone. Ann Clin Biochem 1995;32:345-57.

Ly LP, Sartorius G, Hull L, Leung A, Swerdloff RS, Wang C, Handelsman DJ. Original article: Accuracy of calculated free testosterone formulae in men. Clinical Endocrinology 2010;73:382-

Korábbi áttekintések során használt források

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

(© 2004). Sex Hormone Binding Globulin. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_193b.jsp#1147406 through http://www.arup-lab.com.

(© 2004). Testosterone, Bioavailable and Sex Hormone Binding Globulin. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_225b.jsp#1148913 through http://www.arup-lab.com.

Camillo, P. (2004 January 27). How Should I Handle Complaints of Decreased Libido in Female Patients? Medscape, Ask the Experts about Women's Health for Advanced Practice Nurses [On-line information]. Available online at http://www.medscape.com/viewarticle/466490?src=search through http://www.medscape.com.

Dennerstein, L. (2003 February 12). Depressed Libido in the Postmenopausal Woman. Medscape, Ask the Experts about Menopause [On-line information]. Available online at http://www.medscape.com/viewarticle/448554 through http://www.medscape.com.

Reuters Health (2004 February 4). Postmenopausal Endogenous Hormones Influence Endometrial Cancer Risk. National Cancer Institute [On-line News]. Available online at http://ctep.info.nih.gov/resources/gcig/news020404.html through http://ctep.info.nih.gov.

Tenover, J. (2001). Male Hormone Replacement Therapy Including "Andropause." WellMax.org [On-line News, Essays & Articles]. Available online at http://www.wellmax.org/NewsPub/Stories/2001/05/07/9892607709.html through http://www.wellmax.org.

Patient's Guide to Low Testosterone, 2003 Edition. Medem Medical Library [On-line information by The Hormone Foundation and Endocrine Society]. Available online at http://www.medem.com/medlb/article_detaillb.cfm?article_ID=ZZZO7PDVDLC&sub_cat=57 through http://www.medem.com.

Snyder, P. (2003 September 9). Testes and Testicular Disorders. Medscape, from WebMD Scientific American® Medicine 2003, What's New in Medicine [On-line information]. Available online at http://www.medscape.com/viewarticle/461007 through http://www.medscape.com.

Allan, C. and McLachlan, R. (2004 June 3). Age-Related Changes in Testosterone and the Role of Replacement Therapy in Older Men. Medscape, from Clin Endocrinol 60(6): 653-670, 2004 [On-line journal article]. Available online at http://www.medscape.com/viewarticle/479523?src=search through http://www.medscape.com.

Matsumoto, A. (2008 June 27). Diagnosis and Evaluation of Male Hypogonadism CME. Medscape Today, Selection from: Men's Sexual Health Consult Collection: Testosterone Replacement Therapy in the VA Setting [On-line information]. Available online at http://www.medscape.com/viewarticle/575491 through http://www.medscape.com. Accessed on 7-30-08.

Chang, R. (2007 September 14). The Reproductive Phenotype in Polycystic Ovary Syndrome CME. Medscape From Nature Clinical Practice Endocrinology & Metabolism [On-line information]. Available online at http://www.medscape.com/viewarticle/562712 through http://www.medscape.com. Accessed on 7-30-08.

Sabatini, L. (2007 May 29, Updated). Androgen Excess. emedicine [On-line information]. Available online at http://www.emedicine.com/med/TOPIC3489.HTM through http://www.emedicine.com. Accessed on 7-30-08.

Anawalt, B. (2007 June Reviewed). Male Reproductive Endocrinology, Introduction. Merck Manual for Healthcare Professionals [On-line information]. Available online at http://www.merck.com/mmpe/sec17/ch227/ch227a.html?qt=SHBG&alt=sh through http://www.merck.com. Accessed on 7-30-08.

Anawalt, B. (Revised 2010 January). Male Reproductive Endocrinology. The Merck Manual for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed January 2012.

Dandona, P and Rosenberg, M. (2010 May 10). A Practical Guide to Male Hypogonadism in The Primary Care Setting: Clinical Presentation and Diagnosis. Medscape Today News from Int J Clin Pract. 2010;64(6):682-696 [On-line information]. Available online at http://www.medscape.com/viewarticle/721069_4 through http://www.medscape.com. Accessed January 2012.

Peter, A. et. al. (2010 December 16). Relationships of Circulating Sex Hormone–Binding Globulin with Metabolic Traits in Humans. Medscape Today News from Diabetes. 2010;59 (12) [On-line information]. Available online at http://www.medscape.com/viewarticle/733605 through http://www.medscape.com. Accessed January 2012.

(Updated © 1995-2012). Test ID: SHBG9285 Sex Hormone-Binding Globulin (SHBG), Serum Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/9285 through http://www.mayomedicallaboratories.com. Accessed January 2012.

(Updated 2011 July). Hypogonadism, Male. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/HypogonadismMale.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed January 2012.

Lucidi, R. et. al. (Updated 2011 October 25). Polycystic Ovarian Syndrome. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/256806-overview through http://emedicine.medscape.com. Accessed January 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby’s Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 928-930.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE, eds. St. Louis: Elsevier Saunders; 2006, 2011-2012.

Maggio M, et al. Sex hormone binding globulin levels across the adult lifespan in women - The role of body mass index and fasting insulin. J Endocrinol Invest. 2008 July; 31(7): 597–601. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648802/ through http://www.ncbi.nlm.nih.gov. Accessed February 2012.

Kelly JA, Vankrieeken L. Sex hormone binding globulin and the assessment of androgen status. Available online through http://www.medical.siemens.com. Accessed February 2012.

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Elsewhere On The Web

https://www.hormone.org/diseases-and-conditions/womens-health/polycystic-ovary-…

https://www.hormone.org/diseases-and-conditions/mens-health/low-testosterone

https://medlineplus.gov/ency/article/000369.htm

https://www.cdc.gov/reproductivehealth/Infertility/index.htm

https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosteron…

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